CT-Mapper: Mapping Sparse Multimodal Cellular Trajectories using a Multilayer Transportation Network

Mobile phone data have recently become an attractive source of information about mobility behavior. Since cell phone data can be captured in a passive way for a large user population, they can be harnessed to collect well-sampled mobility information. In this paper, we propose CT-Mapper, an unsupervised algorithm that enables the mapping of mobile phone traces over a multimodal transport network. One of the main strengths of CT-Mapper is its capability to map noisy sparse cellular multimodal trajectories over a multilayer transportation network where the layers have different physical properties and not only to map trajectories associated with a single layer. Such a network is modeled by a large multilayer graph in which the nodes correspond to metro/train stations or road intersections and edges correspond to connections between them. The mapping problem is modeled by an unsupervised HMM where the observations correspond to sparse user mobile trajectories and the hidden states to the multilayer graph nodes. The HMM is unsupervised as the transition and emission probabilities are inferred using respectively the physical transportation properties and the information on the spatial coverage of antenna base stations. To evaluate CT-Mapper we collected cellular traces with their corresponding GPS trajectories for a group of volunteer users in Paris and vicinity (France). We show that CT-Mapper is able to accurately retrieve the real cell phone user paths despite the sparsity of the observed trace trajectories. Furthermore our transition probability model is up to 20% more accurate than other naive models.Comment: Under revision in Computer Communication Journa

Co-production opportunities seized and missed in decision-support frameworks for climate-change adaptation in agriculture – How do we practice the “best practice”?

To contribute to building sustainable and effective climate change adaptation solutions avoiding usability gap, it is largely recommended to engage in the process of co-production, integrating expertise and knowledge from various academic and non-academic actors. We want to learn if and how co-production, believed to effectively link knowledge and decision-making, and thus suggested as the best practice in building decision-support frameworks, is really applied in the frameworks that are being implemented on the ground. A literature review allowed us to identify integrated decision-support frameworks for climate-change adaptation in agriculture developed and used over the period of the last 10 years and involving non-academic stakeholders. To analyse them, we chose as an assessment tool the four co-production principles proposed by Norström and colleagues: context-based, pluralistic, goal-oriented and interactive. The useful entry points for incorporating co-production in the design of decision-support that we found in the reviewed frameworks include among the others adequate participants selection strategy, building on existing interaction spaces, developing a theory of change with the participants, and involving participants in the design of different elements of the method. The architectures of the analyzed frameworks contained more elements that responded to pluralistic and interactive principles than to context-based and goal oriented principles, we have also identified gaps in the design, such as taking into account the personal characteristics of researchers that could strengthen a framework's implementation and its impact, or attempts at bridging different levels of decision making, to cover the triad of science, policy and practice. A detailed look at the decision-frameworks that are actually being applied allows for a critical reflection whether and how we as researchers use what we preach as an effective way of responding to sustainability challenges in agriculture. Co-production principles turn out to be a useful tool for analysis and we suggest they can be used as a check-list when designing decision-support frameworks for climate-change adaptation. This papers offers useful examples of how to shift the research-led processes of decision-support towards more co-production with non-academic actors, to increase chances of bridging the gaps between science, policy and practice

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Methods and analysis tools for human mobility study, based on mobile network signaling data

Cette thèse a pour but d’étudier les activités humaines à travers l’analyse du flux de signalisation du réseau cellulaire de données (GTP). Pour ce faire, nous avons mis en place un ensemble d’outils nous permettant de collecter, stocker et analyser ces données de signalisation. Ceci en se basant sur une architecture indépendante au maximum des constructeurs de matériel. À partir des données extraites par cette plateforme nous avons fait trois contributions.Dans une première contribution, nous présentons l’architecture de la plateforme de capture et d’analyse de la signalisation GTP dans un réseau d’opérateur. Ce travail a pour but de faire l’inventaire des différents éléments déclenchant des mises à jour et aussi d’estimer la précision temporelle et spatiale des données collectées. Ensuite, nous présentons une série de mesures, mettant en avant les caractéristiques principales de la mobilité humaine observées au travers de la signalisation mobile (le temps inter-arrivées des messages de mise à jour, la distance observée des sauts entre cellules lors des déplacements des clients). Finalement, nous présentons l’analyse des compromis qui ont été faits entre la rapidité d’écriture/de lecture et la facilité d’usage du format de fichier utilisé lors de l’échange d’informations entre les sondes de capture et le système stockage. Deuxièmement, nous avons été capables de mettre en place un algorithme de reconstitution de trajets. Cet algorithme permet, à partir de données éparses issues du réseau cellulaire, de forger des trajets sur les voies de transport. Il se base sur les données des trajets sous-échantillonnées et en déduit les positions du client sur les voies de communication. Nous avons mis en place un graphe de transport intermodal. Celui-ci porte sur le métro, le train et le réseau routier. Il connecte les différents points entre eux dans chacune des couches de transport et interconnecte les modes de transport entre eux, aux intersections. Notre algorithme se base sur un modèle de chaîne de Markov cachée pour placer sur le graphe les positions probables des individus entre les différentes observations. L’apport de ce travail est l’utilisation des propriétés topologiques du réseau de transport afin de renseigner les probabilités d’émission et de transition dans un modèle non supervisé. Ces travaux ont donné lieu à une publication et à un brevet. Finalement, notre dernière contribution utilise les données issues de la signalisation à des fins de dimensionnement du réseau mobile d’opérateur. Il s’agit de dimensionner dynamiquement un réseau mobile en utilisant les bandes de fréquences dites vTV-Whitespace. Ces bandes de fréquences sont libérées sous certaines conditions aux USA et soumises à vente aux enchères. Ce que nous proposons est un système basé sur un algorithme de qualité d’expérience (QoE) et sur le coût de la ressource radio afin de choisir où déployer des femtocells supplémentaires et où en supprimer en fonction des variations de population par unité d’espace. En conclusion, cette thèse offre un aperçu du potentiel de l’analyse des metadata de signalisation d’un réseau dans un contexte plus général que la simple supervision d’un réseau d’opérateurThe aim of this thesis is to study human activities through the analysis of the signaling flow in cellular data network (GTP). In order to achieve this goal, we implemented a set of tools allowing us to collect, store and analyze this signaling data. We created an architecture independent at most of hardware manufacturers and network operators. Using data extracted by this platform we made three main contributions. In our first contribution, we present the GTP capture and analysis platform in a mobile operator network. This work intends to list the different elements triggering updates and to estimate the temporal and spatial accuracy of the data collected. Next, we present a set of measures that represent the main characteristics of human mobility observed through the mobile signaling data (the inter-arrival time of update messages, the observed distances of hops from cell to cell made by moving users). Finally, we present the analysis of the compromise that was made between the writing/reading performances and the ease of use of the file format for the data storage. In our second contribution, we propose CT-Mapper, an unsupervised algorithm that enables the mapping of mobile phone traces over a multimodal transport network. One of the main strengths of CT-Mapper is its capability to map noisy sparse cellular multimodal trajectories over a multilayer transportation network where the layers have different physical properties and not only to map trajectories associated with a single layer. Such a network is modeled by a large multilayer graph in which the nodes correspond to metro/train stations or road intersections and edges correspond to connections between them. The mapping problem is modeled by an unsupervised HMM where the observations correspond to sparse user mobile trajectories and the hidden states to the multilayer graph nodes. The HMM is unsupervised as the transition and emission probabilities are inferred using respectively the physical transportation properties and the information on the spatial coverage of antenna base stations. Finally, in our last contribution we propose a method for cellular resource planning taking into account user mobility. Since users move, the bandwidth resource should move accordingly. We design a score based method using TV Whitespace, and user experience, to determine from which cell resource should be removed and to which one it should be added. Combined with traffic history it calculates scores for each cell. Bandwidth is reallocated on a half-day basis. Before that, real traces of cellular networks in urban districts are presented which confirm that static network planning is no longer optimal. A dynamic femtocell architecture is then presented. It is based on mesh interconnected elements and designed to serve the score based bandwidth allocation algorithm. The score method along with the architecture are simulated and results are presented. They confirm the expected improvement in bandwidth and delay per user while maintaining a low operation cost at the operator side. In conclusion, this thesis provides an overview of the potential of analyzing the signaling metadata of a network in a broader context that supervision of an operator networ

Méthodes et outils d'analyse de données de signalisation mobile pour l'étude de la mobilité humaine

The aim of this thesis is to study human activities through the analysis of the signaling flow in cellular data network (GTP). In order to achieve this goal, we implemented a set of tools allowing us to collect, store and analyze this signaling data. We created an architecture independent at most of hardware manufacturers and network operators. Using data extracted by this platform we made three main contributions. In our first contribution, we present the GTP capture and analysis platform in a mobile operator network. This work intends to list the different elements triggering updates and to estimate the temporal and spatial accuracy of the data collected. Next, we present a set of measures that represent the main characteristics of human mobility observed through the mobile signaling data (the inter-arrival time of update messages, the observed distances of hops from cell to cell made by moving users). Finally, we present the analysis of the compromise that was made between the writing/reading performances and the ease of use of the file format for the data storage. In our second contribution, we propose CT-Mapper, an unsupervised algorithm that enables the mapping of mobile phone traces over a multimodal transport network. One of the main strengths of CT-Mapper is its capability to map noisy sparse cellular multimodal trajectories over a multilayer transportation network where the layers have different physical properties and not only to map trajectories associated with a single layer. Such a network is modeled by a large multilayer graph in which the nodes correspond to metro/train stations or road intersections and edges correspond to connections between them. The mapping problem is modeled by an unsupervised HMM where the observations correspond to sparse user mobile trajectories and the hidden states to the multilayer graph nodes. The HMM is unsupervised as the transition and emission probabilities are inferred using respectively the physical transportation properties and the information on the spatial coverage of antenna base stations. Finally, in our last contribution we propose a method for cellular resource planning taking into account user mobility. Since users move, the bandwidth resource should move accordingly. We design a score based method using TV Whitespace, and user experience, to determine from which cell resource should be removed and to which one it should be added. Combined with traffic history it calculates scores for each cell. Bandwidth is reallocated on a half-day basis. Before that, real traces of cellular networks in urban districts are presented which confirm that static network planning is no longer optimal. A dynamic femtocell architecture is then presented. It is based on mesh interconnected elements and designed to serve the score based bandwidth allocation algorithm. The score method along with the architecture are simulated and results are presented. They confirm the expected improvement in bandwidth and delay per user while maintaining a low operation cost at the operator side. In conclusion, this thesis provides an overview of the potential of analyzing the signaling metadata of a network in a broader context that supervision of an operator networkCette thèse a pour but d’étudier les activités humaines à travers l’analyse du flux de signalisation du réseau cellulaire de données (GTP). Pour ce faire, nous avons mis en place un ensemble d’outils nous permettant de collecter, stocker et analyser ces données de signalisation. Ceci en se basant sur une architecture indépendante au maximum des constructeurs de matériel. À partir des données extraites par cette plateforme nous avons fait trois contributions.Dans une première contribution, nous présentons l’architecture de la plateforme de capture et d’analyse de la signalisation GTP dans un réseau d’opérateur. Ce travail a pour but de faire l’inventaire des différents éléments déclenchant des mises à jour et aussi d’estimer la précision temporelle et spatiale des données collectées. Ensuite, nous présentons une série de mesures, mettant en avant les caractéristiques principales de la mobilité humaine observées au travers de la signalisation mobile (le temps inter-arrivées des messages de mise à jour, la distance observée des sauts entre cellules lors des déplacements des clients). Finalement, nous présentons l’analyse des compromis qui ont été faits entre la rapidité d’écriture/de lecture et la facilité d’usage du format de fichier utilisé lors de l’échange d’informations entre les sondes de capture et le système stockage. Deuxièmement, nous avons été capables de mettre en place un algorithme de reconstitution de trajets. Cet algorithme permet, à partir de données éparses issues du réseau cellulaire, de forger des trajets sur les voies de transport. Il se base sur les données des trajets sous-échantillonnées et en déduit les positions du client sur les voies de communication. Nous avons mis en place un graphe de transport intermodal. Celui-ci porte sur le métro, le train et le réseau routier. Il connecte les différents points entre eux dans chacune des couches de transport et interconnecte les modes de transport entre eux, aux intersections. Notre algorithme se base sur un modèle de chaîne de Markov cachée pour placer sur le graphe les positions probables des individus entre les différentes observations. L’apport de ce travail est l’utilisation des propriétés topologiques du réseau de transport afin de renseigner les probabilités d’émission et de transition dans un modèle non supervisé. Ces travaux ont donné lieu à une publication et à un brevet. Finalement, notre dernière contribution utilise les données issues de la signalisation à des fins de dimensionnement du réseau mobile d’opérateur. Il s’agit de dimensionner dynamiquement un réseau mobile en utilisant les bandes de fréquences dites vTV-Whitespace. Ces bandes de fréquences sont libérées sous certaines conditions aux USA et soumises à vente aux enchères. Ce que nous proposons est un système basé sur un algorithme de qualité d’expérience (QoE) et sur le coût de la ressource radio afin de choisir où déployer des femtocells supplémentaires et où en supprimer en fonction des variations de population par unité d’espace. En conclusion, cette thèse offre un aperçu du potentiel de l’analyse des metadata de signalisation d’un réseau dans un contexte plus général que la simple supervision d’un réseau d’opérateu

Weather-index drought insurance in Burkina-Faso: assessment of its potential interest to farmers

International audienc

Including tropical croplands in a terrestrial biosphere model: application to West Africa

International audienc